# Anthropic medicinal-chemistry evaluation (Medicinal chemistry)

> Selects compounds with the highest or lowest measured ADME-related property from molecular structures and reference values.

Canonical page: https://benchlm.ai/benchmarks/medicinalchemistry

- Category: [Knowledge](/knowledge)
- Last updated: September 27, 2026

## About Medicinal chemistry

- Year: 2026
- Tasks: 504 molecular-property questions
- Format: Accuracy
- Difficulty: Medicinal chemistry reasoning
- Paper: [Claude Opus 5.5 System Card](https://www-cdn.anthropic.com/fc1b44717c85dc068bc6ba5024219938094694bd/Claude%20Opus%205.5%20System%20Card.pdf)

Section 8.17.4 reports a provider-run five-attempt average across 504 questions without tools. It is display-only evidence.

Medicinal chemistry is currently displayed on BenchLM for reference, but it is excluded from the weighted scoring formula.

## Leaderboard (1 models)

| Rank | Model | Creator | Score |
|------|-------|---------|-------|
| 1 | [Claude Opus 5.5](/models/claude-opus-5-5) | Anthropic | 63.5% |

## FAQ

### What does Medicinal chemistry measure?

Selects compounds with the highest or lowest measured ADME-related property from molecular structures and reference values.

### Which model scores highest on Medicinal chemistry?

Claude Opus 5.5 by Anthropic currently leads with a score of 63.5% on Medicinal chemistry.

### How many models are evaluated on Medicinal chemistry?

1 AI models have been evaluated on Medicinal chemistry on BenchLM.

### Does Medicinal chemistry affect BenchLM's overall score?

Not directly. Medicinal chemistry is still displayed on BenchLM for reference, but it is excluded from the weighted scoring formula.