# LatchBio SingleCellBench (SingleCellBench)

> Single-cell RNA sequencing analysis tasks spanning common bioinformatics workflows.

Canonical page: https://benchlm.ai/benchmarks/singlecellbench

- Category: [Knowledge](/knowledge)
- Last updated: September 27, 2026

## About SingleCellBench

- Year: 2026
- Tasks: 195 single-cell RNA sequencing problems
- Format: Task score
- Difficulty: Professional bioinformatics
- Paper: [Claude Opus 5 System Card](https://www-cdn.anthropic.com/c5fbac3f0b1280a933ebd26d3cb8bb9f5bdeaf48/Claude%20Opus%205%20System%20Card.pdf)

Section 8.17.2 reports this provider-run result as display-only life-science evidence.

SingleCellBench is currently displayed on BenchLM for reference, but it is excluded from the weighted scoring formula.

## Leaderboard (2 models)

| Rank | Model | Creator | Score |
|------|-------|---------|-------|
| 1 | [Claude Opus 5.5](/models/claude-opus-5-5) | Anthropic | 61.2% |
| 2 | [Claude Opus 5](/models/claude-opus-5) | Anthropic | 60.6% |

## FAQ

### What does SingleCellBench measure?

Single-cell RNA sequencing analysis tasks spanning common bioinformatics workflows.

### Which model scores highest on SingleCellBench?

Claude Opus 5.5 by Anthropic currently leads with a score of 61.2% on SingleCellBench.

### How many models are evaluated on SingleCellBench?

2 AI models have been evaluated on SingleCellBench on BenchLM.

### Does SingleCellBench affect BenchLM's overall score?

Not directly. SingleCellBench is still displayed on BenchLM for reference, but it is excluded from the weighted scoring formula.

## Compare Top Models on SingleCellBench

- [Claude Opus 5.5 vs Claude Opus 5](/compare/claude-opus-5-vs-claude-opus-5-5)