Claude 3 Opus vs Mixtral 8x22B Instruct v0.1

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Claude 3 Opus is clearly ahead on the aggregate, 53 to 28. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

Claude 3 Opus gives you the larger context window at 200K, compared with 64K for Mixtral 8x22B Instruct v0.1.

Quick Verdict

Pick Claude 3 Opus if you want the stronger benchmark profile. Mixtral 8x22B Instruct v0.1 only becomes the better choice if coding is the priority.

Knowledge

Mixtral 8x22B Instruct v0.1

Claude 3 Opus

50.2

Mixtral 8x22B Instruct v0.1

71.4

61
MMLU
71.4
61
GPQA
-
59
SuperGPQA
-
57
OpenBookQA
-
62
MMLU-Pro
-
1
HLE
-

Coding

Mixtral 8x22B Instruct v0.1

Claude 3 Opus

27.7

Mixtral 8x22B Instruct v0.1

54.8

53
HumanEval
54.8
10
SWE-bench Verified
-
20
LiveCodeBench
-

Mathematics

Claude 3 Opus
61
AIME 2023
-
63
AIME 2024
-
62
AIME 2025
-
57
HMMT Feb 2023
-
59
HMMT Feb 2024
-
58
HMMT Feb 2025
-
60
BRUMO 2025
-
73
MATH-500
-

Reasoning

Claude 3 Opus
59
SimpleQA
-
57
MuSR
-
74
BBH
-

Instruction Following

Claude 3 Opus
77
IFEval
-

Multilingual

Claude 3 Opus
73
MGSM
-

Frequently Asked Questions

Which is better, Claude 3 Opus or Mixtral 8x22B Instruct v0.1?

Claude 3 Opus is ahead overall, 53 to 28. The biggest single separator in this matchup is MMLU, where the scores are 61 and 71.4.

Which is better for knowledge tasks, Claude 3 Opus or Mixtral 8x22B Instruct v0.1?

Mixtral 8x22B Instruct v0.1 has the edge for knowledge tasks in this comparison, averaging 71.4 versus 50.2. Inside this category, MMLU is the benchmark that creates the most daylight between them.

Which is better for coding, Claude 3 Opus or Mixtral 8x22B Instruct v0.1?

Mixtral 8x22B Instruct v0.1 has the edge for coding in this comparison, averaging 54.8 versus 27.7. Inside this category, HumanEval is the benchmark that creates the most daylight between them.

Last updated: March 9, 2026

Weekly LLM Benchmark Digest

Get notified when new models drop, benchmark scores change, or the leaderboard shifts. One email per week.

Free. No spam. Unsubscribe anytime. We only store derived location metadata for consent routing.