Claude Opus 4.5 vs Seed-2.0-Lite

Side-by-side benchmark comparison across agentic, coding, multimodal, knowledge, reasoning, and math workflows.

Claude Opus 4.5 is clearly ahead on the aggregate, 77 to 63. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

Claude Opus 4.5's sharpest advantage is in coding, where it averages 60.4 against 41.4. The single biggest benchmark swing on the page is HumanEval, 91 to 63.

Seed-2.0-Lite gives you the larger context window at 256K, compared with 200K for Claude Opus 4.5.

Quick Verdict

Pick Claude Opus 4.5 if you want the stronger benchmark profile. Seed-2.0-Lite only becomes the better choice if you need the larger 256K context window.

Agentic

Claude Opus 4.5

Claude Opus 4.5

70.5

Seed-2.0-Lite

55.1

71
Terminal-Bench 2.0
52
73
BrowseComp
63
68
OSWorld-Verified
53

Coding

Claude Opus 4.5

Claude Opus 4.5

60.4

Seed-2.0-Lite

41.4

91
HumanEval
63
68
SWE-bench Verified
45
57
LiveCodeBench
37
62
SWE-bench Pro
45

Multimodal & Grounded

Claude Opus 4.5

Claude Opus 4.5

90.9

Seed-2.0-Lite

79.6

94
MMMU-Pro
80
87
OfficeQA Pro
79

Reasoning

Claude Opus 4.5

Claude Opus 4.5

87.7

Seed-2.0-Lite

73

95
SimpleQA
68
93
MuSR
66
87
BBH
85
82
LongBench v2
76
81
MRCRv2
77

Knowledge

Claude Opus 4.5

Claude Opus 4.5

70.9

Seed-2.0-Lite

53.9

99
MMLU
71
97
GPQA
70
95
SuperGPQA
68
93
OpenBookQA
66
81
MMLU-Pro
73
20
HLE
7
84
FrontierScience
66

Instruction Following

Claude Opus 4.5

Claude Opus 4.5

90

Seed-2.0-Lite

89

90
IFEval
89

Multilingual

Claude Opus 4.5

Claude Opus 4.5

86.1

Seed-2.0-Lite

82.5

90
MGSM
87
84
MMLU-ProX
80

Mathematics

Claude Opus 4.5

Claude Opus 4.5

93.2

Seed-2.0-Lite

75

99
AIME 2023
71
99
AIME 2024
73
98
AIME 2025
72
95
HMMT Feb 2023
67
97
HMMT Feb 2024
69
96
HMMT Feb 2025
68
96
BRUMO 2025
70
89
MATH-500
81

Frequently Asked Questions

Which is better, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 is ahead overall, 77 to 63. The biggest single separator in this matchup is HumanEval, where the scores are 91 and 63.

Which is better for knowledge tasks, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for knowledge tasks in this comparison, averaging 70.9 versus 53.9. Inside this category, MMLU is the benchmark that creates the most daylight between them.

Which is better for coding, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for coding in this comparison, averaging 60.4 versus 41.4. Inside this category, HumanEval is the benchmark that creates the most daylight between them.

Which is better for math, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for math in this comparison, averaging 93.2 versus 75. Inside this category, AIME 2023 is the benchmark that creates the most daylight between them.

Which is better for reasoning, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for reasoning in this comparison, averaging 87.7 versus 73. Inside this category, SimpleQA is the benchmark that creates the most daylight between them.

Which is better for agentic tasks, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for agentic tasks in this comparison, averaging 70.5 versus 55.1. Inside this category, Terminal-Bench 2.0 is the benchmark that creates the most daylight between them.

Which is better for multimodal and grounded tasks, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for multimodal and grounded tasks in this comparison, averaging 90.9 versus 79.6. Inside this category, MMMU-Pro is the benchmark that creates the most daylight between them.

Which is better for instruction following, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for instruction following in this comparison, averaging 90 versus 89. Inside this category, IFEval is the benchmark that creates the most daylight between them.

Which is better for multilingual tasks, Claude Opus 4.5 or Seed-2.0-Lite?

Claude Opus 4.5 has the edge for multilingual tasks in this comparison, averaging 86.1 versus 82.5. Inside this category, MMLU-ProX is the benchmark that creates the most daylight between them.

Last updated: March 12, 2026

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