o1-pro vs Mixtral 8x22B Instruct v0.1

Side-by-side benchmark comparison across agentic, coding, multimodal, knowledge, reasoning, and math workflows.

o1-pro is clearly ahead on the aggregate, 45 to 35. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

o1-pro's sharpest advantage is in reasoning, where it averages 56.2 against 38.6. The single biggest benchmark swing on the page is MRCRv2, 59 to 38. Mixtral 8x22B Instruct v0.1 does hit back in coding, so the answer changes if that is the part of the workload you care about most.

o1-pro is also the more expensive model on tokens at $150.00 input / $600.00 output per 1M tokens, versus $0.00 input / $0.00 output per 1M tokens for Mixtral 8x22B Instruct v0.1. That is roughly Infinityx on output cost alone. o1-pro is the reasoning model in the pair, while Mixtral 8x22B Instruct v0.1 is not. That usually helps on harder chain-of-thought-heavy tests, but it can also mean more latency and more token spend in real use. o1-pro gives you the larger context window at 200K, compared with 64K for Mixtral 8x22B Instruct v0.1.

Quick Verdict

Pick o1-pro if you want the stronger benchmark profile. Mixtral 8x22B Instruct v0.1 only becomes the better choice if coding is the priority or you want the cheaper token bill.

Agentic

o1-pro

o1-pro

39.7

Mixtral 8x22B Instruct v0.1

31.8

40
Terminal-Bench 2.0
35
50
BrowseComp
32
32
OSWorld-Verified
28

Coding

Mixtral 8x22B Instruct v0.1

o1-pro

23

Mixtral 8x22B Instruct v0.1

40

23
SWE-bench Pro
40
Coming soon
HumanEval
54.8

Multimodal & Grounded

o1-pro

o1-pro

48.5

Mixtral 8x22B Instruct v0.1

35.5

48
MMMU-Pro
35
49
OfficeQA Pro
36

Reasoning

o1-pro

o1-pro

56.2

Mixtral 8x22B Instruct v0.1

38.6

54
LongBench v2
39
59
MRCRv2
38

Knowledge

o1-pro

o1-pro

69.9

Mixtral 8x22B Instruct v0.1

53

79
GPQA
Coming soon
63
FrontierScience
53
Coming soon
MMLU
71.4

Instruction Following

Coming soon

Benchmark data for this category is coming soon.

Multilingual

o1-pro

o1-pro

52

Mixtral 8x22B Instruct v0.1

42

52
MMLU-ProX
42

Mathematics

Coming soon

Comparable scores for this category are coming soon. One or both models do not have sourced results here yet.

86
AIME 2024
Coming soon

Frequently Asked Questions

Which is better, o1-pro or Mixtral 8x22B Instruct v0.1?

o1-pro is ahead overall, 45 to 35. The biggest single separator in this matchup is MRCRv2, where the scores are 59 and 38.

Which is better for knowledge tasks, o1-pro or Mixtral 8x22B Instruct v0.1?

o1-pro has the edge for knowledge tasks in this comparison, averaging 69.9 versus 53. Inside this category, FrontierScience is the benchmark that creates the most daylight between them.

Which is better for coding, o1-pro or Mixtral 8x22B Instruct v0.1?

Mixtral 8x22B Instruct v0.1 has the edge for coding in this comparison, averaging 40 versus 23. Inside this category, SWE-bench Pro is the benchmark that creates the most daylight between them.

Which is better for reasoning, o1-pro or Mixtral 8x22B Instruct v0.1?

o1-pro has the edge for reasoning in this comparison, averaging 56.2 versus 38.6. Inside this category, MRCRv2 is the benchmark that creates the most daylight between them.

Which is better for agentic tasks, o1-pro or Mixtral 8x22B Instruct v0.1?

o1-pro has the edge for agentic tasks in this comparison, averaging 39.7 versus 31.8. Inside this category, BrowseComp is the benchmark that creates the most daylight between them.

Which is better for multimodal and grounded tasks, o1-pro or Mixtral 8x22B Instruct v0.1?

o1-pro has the edge for multimodal and grounded tasks in this comparison, averaging 48.5 versus 35.5. Inside this category, MMMU-Pro is the benchmark that creates the most daylight between them.

Which is better for multilingual tasks, o1-pro or Mixtral 8x22B Instruct v0.1?

o1-pro has the edge for multilingual tasks in this comparison, averaging 52 versus 42. Inside this category, MMLU-ProX is the benchmark that creates the most daylight between them.

Last updated: March 12, 2026

Weekly LLM Benchmark Digest

Get notified when new models drop, benchmark scores change, or the leaderboard shifts. One email per week.

Free. No spam. Unsubscribe anytime. We only store derived location metadata for consent routing.