Qwen2.5-72B vs GPT-4.1 mini

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Qwen2.5-72B is clearly ahead on the aggregate, 72 to 35. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

Qwen2.5-72B's sharpest advantage is in mathematics, where it averages 83.1 against 23.1. The single biggest benchmark swing on the page is AIME 2024, 86 to 23.1. GPT-4.1 mini does hit back in knowledge, so the answer changes if that is the part of the workload you care about most.

GPT-4.1 mini gives you the larger context window at 1M, compared with 128K for Qwen2.5-72B.

Quick Verdict

Pick Qwen2.5-72B if you want the stronger benchmark profile. GPT-4.1 mini only becomes the better choice if knowledge is the priority or you need the larger 1M context window.

Knowledge

GPT-4.1 mini

Qwen2.5-72B

68.2

GPT-4.1 mini

75.9

83
MMLU
87.5
82
GPQA
64.2
80
SuperGPQA
-
78
OpenBookQA
-
75
MMLU-Pro
-
11
HLE
-

Coding

Qwen2.5-72B

Qwen2.5-72B

53.7

GPT-4.1 mini

23.6

75
HumanEval
-
46
SWE-bench Verified
23.6
40
LiveCodeBench
-

Mathematics

Qwen2.5-72B

Qwen2.5-72B

83.1

GPT-4.1 mini

23.1

84
AIME 2023
-
86
AIME 2024
23.1
85
AIME 2025
-
80
HMMT Feb 2023
-
82
HMMT Feb 2024
-
81
HMMT Feb 2025
-
83
BRUMO 2025
-
84
MATH-500
-

Reasoning

Qwen2.5-72B
80
SimpleQA
-
78
MuSR
-
81
BBH
-

Instruction Following

GPT-4.1 mini

Qwen2.5-72B

85

GPT-4.1 mini

88.5

85
IFEval
88.5

Multilingual

Qwen2.5-72B
84
MGSM
-

Frequently Asked Questions

Which is better, Qwen2.5-72B or GPT-4.1 mini?

Qwen2.5-72B is ahead overall, 72 to 35. The biggest single separator in this matchup is AIME 2024, where the scores are 86 and 23.1.

Which is better for knowledge tasks, Qwen2.5-72B or GPT-4.1 mini?

GPT-4.1 mini has the edge for knowledge tasks in this comparison, averaging 75.9 versus 68.2. Inside this category, GPQA is the benchmark that creates the most daylight between them.

Which is better for coding, Qwen2.5-72B or GPT-4.1 mini?

Qwen2.5-72B has the edge for coding in this comparison, averaging 53.7 versus 23.6. Inside this category, SWE-bench Verified is the benchmark that creates the most daylight between them.

Which is better for math, Qwen2.5-72B or GPT-4.1 mini?

Qwen2.5-72B has the edge for math in this comparison, averaging 83.1 versus 23.1. Inside this category, AIME 2024 is the benchmark that creates the most daylight between them.

Which is better for instruction following, Qwen2.5-72B or GPT-4.1 mini?

GPT-4.1 mini has the edge for instruction following in this comparison, averaging 88.5 versus 85. Inside this category, IFEval is the benchmark that creates the most daylight between them.

Last updated: March 9, 2026

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