Qwen2.5-72B vs GPT-4.1 nano

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Qwen2.5-72B is clearly ahead on the aggregate, 72 to 23. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

Qwen2.5-72B's sharpest advantage is in mathematics, where it averages 83.1 against 9.8. The single biggest benchmark swing on the page is AIME 2024, 86 to 9.8.

GPT-4.1 nano gives you the larger context window at 1M, compared with 128K for Qwen2.5-72B.

Quick Verdict

Pick Qwen2.5-72B if you want the stronger benchmark profile. GPT-4.1 nano only becomes the better choice if you need the larger 1M context window.

Knowledge

Qwen2.5-72B

Qwen2.5-72B

68.2

GPT-4.1 nano

65.2

83
MMLU
80.1
82
GPQA
50.3
80
SuperGPQA
-
78
OpenBookQA
-
75
MMLU-Pro
-
11
HLE
-

Coding

Qwen2.5-72B
75
HumanEval
-
46
SWE-bench Verified
-
40
LiveCodeBench
-

Mathematics

Qwen2.5-72B

Qwen2.5-72B

83.1

GPT-4.1 nano

9.8

84
AIME 2023
-
86
AIME 2024
9.8
85
AIME 2025
-
80
HMMT Feb 2023
-
82
HMMT Feb 2024
-
81
HMMT Feb 2025
-
83
BRUMO 2025
-
84
MATH-500
-

Reasoning

Qwen2.5-72B
80
SimpleQA
-
78
MuSR
-
81
BBH
-

Instruction Following

Qwen2.5-72B

Qwen2.5-72B

85

GPT-4.1 nano

83.2

85
IFEval
83.2

Multilingual

Qwen2.5-72B
84
MGSM
-

Frequently Asked Questions

Which is better, Qwen2.5-72B or GPT-4.1 nano?

Qwen2.5-72B is ahead overall, 72 to 23. The biggest single separator in this matchup is AIME 2024, where the scores are 86 and 9.8.

Which is better for knowledge tasks, Qwen2.5-72B or GPT-4.1 nano?

Qwen2.5-72B has the edge for knowledge tasks in this comparison, averaging 68.2 versus 65.2. Inside this category, GPQA is the benchmark that creates the most daylight between them.

Which is better for math, Qwen2.5-72B or GPT-4.1 nano?

Qwen2.5-72B has the edge for math in this comparison, averaging 83.1 versus 9.8. Inside this category, AIME 2024 is the benchmark that creates the most daylight between them.

Which is better for instruction following, Qwen2.5-72B or GPT-4.1 nano?

Qwen2.5-72B has the edge for instruction following in this comparison, averaging 85 versus 83.2. Inside this category, IFEval is the benchmark that creates the most daylight between them.

Last updated: March 9, 2026

Weekly LLM Benchmark Digest

Get notified when new models drop, benchmark scores change, or the leaderboard shifts. One email per week.

Free. No spam. Unsubscribe anytime. We only store derived location metadata for consent routing.