Claude 4.1 Opus Thinking vs Claude Sonnet 4.5

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

Claude Sonnet 4.5 wins overall with a score of 74 vs 29 (45 point difference).Claude Sonnet 4.5 wins 4 out of 4 categories.

Knowledge

Claude Sonnet 4.5

Claude 4.1 Opus Thinking

35.8

Claude Sonnet 4.5

92

38
MMLU
95
37
GPQA
93
35
SuperGPQA
91
33
OpenBookQA
89

Coding

Claude Sonnet 4.5

Claude 4.1 Opus Thinking

30

Claude Sonnet 4.5

87

30
HumanEval
87

Mathematics

Claude Sonnet 4.5

Claude 4.1 Opus Thinking

37

Claude Sonnet 4.5

96

38
AIME 2023
97
40
AIME 2024
99
39
AIME 2025
98
34
HMMT Feb 2023
93
36
HMMT Feb 2024
95
35
HMMT Feb 2025
94
37
BRUMO 2025
96

Reasoning

Claude Sonnet 4.5

Claude 4.1 Opus Thinking

35

Claude Sonnet 4.5

90

36
SimpleQA
91
34
MuSR
89

Frequently Asked Questions

Which is better, Claude 4.1 Opus Thinking or Claude Sonnet 4.5?

Claude Sonnet 4.5 scores higher overall with 74 vs 29, a difference of 45 points across all benchmarks.

Which is better for knowledge tasks, Claude 4.1 Opus Thinking or Claude Sonnet 4.5?

Claude Sonnet 4.5 leads in knowledge tasks with an average score of 92 vs 35.8.

Which is better for coding, Claude 4.1 Opus Thinking or Claude Sonnet 4.5?

Claude Sonnet 4.5 leads in coding with an average score of 87 vs 30.

Which is better for math, Claude 4.1 Opus Thinking or Claude Sonnet 4.5?

Claude Sonnet 4.5 leads in math with an average score of 96 vs 37.

Which is better for reasoning, Claude 4.1 Opus Thinking or Claude Sonnet 4.5?

Claude Sonnet 4.5 leads in reasoning with an average score of 90 vs 35.