Claude 4.1 Opus Thinking vs GPT-4o

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

GPT-4o wins overall with a score of 56 vs 29 (27 point difference).GPT-4o wins 4 out of 4 categories.

Knowledge

GPT-4o

Claude 4.1 Opus Thinking

35.8

GPT-4o

64.5

38
MMLU
66
37
GPQA
66
35
SuperGPQA
64
33
OpenBookQA
62

Coding

GPT-4o

Claude 4.1 Opus Thinking

30

GPT-4o

58

30
HumanEval
58

Mathematics

GPT-4o

Claude 4.1 Opus Thinking

37

GPT-4o

65

38
AIME 2023
66
40
AIME 2024
68
39
AIME 2025
67
34
HMMT Feb 2023
62
36
HMMT Feb 2024
64
35
HMMT Feb 2025
63
37
BRUMO 2025
65

Reasoning

GPT-4o

Claude 4.1 Opus Thinking

35

GPT-4o

63

36
SimpleQA
64
34
MuSR
62

Frequently Asked Questions

Which is better, Claude 4.1 Opus Thinking or GPT-4o?

GPT-4o scores higher overall with 56 vs 29, a difference of 27 points across all benchmarks.

Which is better for knowledge tasks, Claude 4.1 Opus Thinking or GPT-4o?

GPT-4o leads in knowledge tasks with an average score of 64.5 vs 35.8.

Which is better for coding, Claude 4.1 Opus Thinking or GPT-4o?

GPT-4o leads in coding with an average score of 58 vs 30.

Which is better for math, Claude 4.1 Opus Thinking or GPT-4o?

GPT-4o leads in math with an average score of 65 vs 37.

Which is better for reasoning, Claude 4.1 Opus Thinking or GPT-4o?

GPT-4o leads in reasoning with an average score of 63 vs 35.