Anthropic protein-design library-ranking task (Protein Design library ranking)
We show this table for reference; we do not rank on it.
Ranks held-out protein designs for experimental testing using wet-lab campaign measurements and a selection objective.
Benchmark score on Protein Design library ranking — November 13, 2026
We compile the Protein Design library ranking rows from provider self-reports. Claude Opus 5.5 leads the table at 56.0%, followed by Claude Sonnet 5.5 (54.8%). We do not use these results to rank models overall.
Claude Opus 5.5
Anthropic
Reported by AnthropicClaude Sonnet 5.5
Anthropic
Reported by Anthropic2 modelsKnowledgeCurrentDisplay onlyUpdated November 13, 2026
Benchmark score table (2 models)
All 2 results on this page were reported by the labs that built the models.
| Rank | Model / configuration | Score | Who ran it | Parameters (B) | Open / closed |
|---|---|---|---|---|---|
| 1 | Claude Opus 5.5AnthropicReported by Anthropic | 56.0% | Reported by Anthropic | Not reported | Closed |
| 2 | Claude Sonnet 5.5AnthropicReported by Anthropic | 54.8% | Reported by Anthropic | Not reported | Closed |
- Lab-reported
- Benchmark-run
- Independent
About Protein Design library ranking
Year
2026
Tasks
83 protein-design library-ranking problems
Format
Chance-normalized average precision
Difficulty
Computational protein design
Section 8.17.5 reports chance-normalized average precision across the current 83-problem version. Earlier system-card results use a different problem set and grader, so this lane remains distinct and display-only.
Freshness and provenance
Version
Protein Design library ranking 2026
Refresh cadence
Quarterly
Staleness state
Current
Question availability
Public benchmark set
BenchLM uses freshness metadata to decide whether a benchmark should still be treated as a strong differentiator, a benchmark to watch, or a display-only reference. For the full scoring policy, see the BenchLM methodology page.
Questions
What does Protein Design library ranking measure?
Ranks held-out protein designs for experimental testing using wet-lab campaign measurements and a selection objective.
Which model scores highest on Protein Design library ranking?
Claude Opus 5.5 by Anthropic currently leads with a score of 56.0% on Protein Design library ranking.
How many models are evaluated on Protein Design library ranking?
2 AI models have published results on Protein Design library ranking in the BenchLM catalog.
Compare top models on Protein Design library ranking
Know when it’s worth switching models
The model to choose, the cheaper alternative, and the release we would wait on.
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