Benchling Molecular Biology Protocols Understanding (Protocols (understanding))
We show this table for reference; we do not rank on it.
Extends online molecular-biology protocols in additional directions using document and web-search tools.
Benchmark score on Protocols (understanding) — November 13, 2026
We compile the Protocols (understanding) rows from provider self-reports. Claude Opus 5 leads the table at 78.4%, followed by Claude Opus 5.5 (69.0%) and Claude Sonnet 5.5 (66.6%). We do not use these results to rank models overall.
Claude Opus 5
Anthropic
Reported by AnthropicClaude Opus 5.5
Anthropic
Reported by AnthropicClaude Sonnet 5.5
Anthropic
Reported by Anthropic3 modelsKnowledgeCurrentDisplay onlyUpdated November 13, 2026
Benchmark score table (3 models)
All 3 results on this page were reported by the labs that built the models.
| Rank | Model / configuration | Score | Who ran it | Parameters (B) | Open / closed |
|---|---|---|---|---|---|
| 1 | Claude Opus 5AnthropicReported by Anthropic | 78.4% | Reported by Anthropic | Not reported | Closed |
| 2 | Claude Opus 5.5AnthropicReported by Anthropic | 69.0% | Reported by Anthropic | Not reported | Closed |
| 3 | Claude Sonnet 5.5AnthropicReported by Anthropic | 66.6% | Reported by Anthropic | Not reported | Closed |
- Lab-reported
- Benchmark-run
- Independent
Among the reported Protocols (understanding) rows, Claude Opus 5 is first at 78.4%. The third row is 11.8 points behind. The broader top-10 range is 11.8 points, so the table still separates the published systems.
3 models have been evaluated on Protocols (understanding). The benchmark falls in the Knowledge category. Protocols (understanding) is currently displayed for reference but excluded from the scoring formula, so it does not directly affect overall rankings.
About Protocols (understanding)
Year
2026
Tasks
Molecular-biology protocol extension
Format
Task score
Difficulty
Expert laboratory protocols
Section 8.17.6 reports the Benchling-created understanding variant separately from troubleshooting.
Freshness and provenance
Version
Protocols (understanding) 2026
Refresh cadence
Quarterly
Staleness state
Current
Question availability
Public benchmark set
BenchLM uses freshness metadata to decide whether a benchmark should still be treated as a strong differentiator, a benchmark to watch, or a display-only reference. For the full scoring policy, see the BenchLM methodology page.
Questions
What does Protocols (understanding) measure?
Extends online molecular-biology protocols in additional directions using document and web-search tools.
Which model scores highest on Protocols (understanding)?
Claude Opus 5 by Anthropic currently leads with a score of 78.4% on Protocols (understanding).
How many models are evaluated on Protocols (understanding)?
3 AI models have published results on Protocols (understanding) in the BenchLM catalog.
Compare top models on Protocols (understanding)
Know when it’s worth switching models
The model to choose, the cheaper alternative, and the release we would wait on.
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