Claude 4.1 Opus vs GPT-5 (medium)

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

GPT-5 (medium) wins overall with a score of 70 vs 61 (9 point difference).GPT-5 (medium) wins 4 out of 4 categories.

Knowledge

GPT-5 (medium)

Claude 4.1 Opus

74.5

GPT-5 (medium)

88

76
MMLU
91
76
GPQA
89
74
SuperGPQA
87
72
OpenBookQA
85

Coding

GPT-5 (medium)

Claude 4.1 Opus

68

GPT-5 (medium)

83

68
HumanEval
83

Mathematics

GPT-5 (medium)

Claude 4.1 Opus

75

GPT-5 (medium)

92

76
AIME 2023
93
78
AIME 2024
95
77
AIME 2025
94
72
HMMT Feb 2023
89
74
HMMT Feb 2024
91
73
HMMT Feb 2025
90
75
BRUMO 2025
92

Reasoning

GPT-5 (medium)

Claude 4.1 Opus

73

GPT-5 (medium)

86

74
SimpleQA
87
72
MuSR
85

Frequently Asked Questions

Which is better, Claude 4.1 Opus or GPT-5 (medium)?

GPT-5 (medium) scores higher overall with 70 vs 61, a difference of 9 points across all benchmarks.

Which is better for knowledge tasks, Claude 4.1 Opus or GPT-5 (medium)?

GPT-5 (medium) leads in knowledge tasks with an average score of 88 vs 74.5.

Which is better for coding, Claude 4.1 Opus or GPT-5 (medium)?

GPT-5 (medium) leads in coding with an average score of 83 vs 68.

Which is better for math, Claude 4.1 Opus or GPT-5 (medium)?

GPT-5 (medium) leads in math with an average score of 92 vs 75.

Which is better for reasoning, Claude 4.1 Opus or GPT-5 (medium)?

GPT-5 (medium) leads in reasoning with an average score of 86 vs 73.