Claude Sonnet 4.5 vs Qwen2.5-72B

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

Claude Sonnet 4.5 wins overall with a score of 74 vs 65 (9 point difference).Claude Sonnet 4.5 wins 4 out of 4 categories.

Knowledge

Claude Sonnet 4.5

Claude Sonnet 4.5

92

Qwen2.5-72B

80.8

95
MMLU
83
93
GPQA
82
91
SuperGPQA
80
89
OpenBookQA
78

Coding

Claude Sonnet 4.5

Claude Sonnet 4.5

87

Qwen2.5-72B

75

87
HumanEval
75

Mathematics

Claude Sonnet 4.5

Claude Sonnet 4.5

96

Qwen2.5-72B

83

97
AIME 2023
84
99
AIME 2024
86
98
AIME 2025
85
93
HMMT Feb 2023
80
95
HMMT Feb 2024
82
94
HMMT Feb 2025
81
96
BRUMO 2025
83

Reasoning

Claude Sonnet 4.5

Claude Sonnet 4.5

90

Qwen2.5-72B

79

91
SimpleQA
80
89
MuSR
78

Frequently Asked Questions

Which is better, Claude Sonnet 4.5 or Qwen2.5-72B?

Claude Sonnet 4.5 scores higher overall with 74 vs 65, a difference of 9 points across all benchmarks.

Which is better for knowledge tasks, Claude Sonnet 4.5 or Qwen2.5-72B?

Claude Sonnet 4.5 leads in knowledge tasks with an average score of 92 vs 80.8.

Which is better for coding, Claude Sonnet 4.5 or Qwen2.5-72B?

Claude Sonnet 4.5 leads in coding with an average score of 87 vs 75.

Which is better for math, Claude Sonnet 4.5 or Qwen2.5-72B?

Claude Sonnet 4.5 leads in math with an average score of 96 vs 83.

Which is better for reasoning, Claude Sonnet 4.5 or Qwen2.5-72B?

Claude Sonnet 4.5 leads in reasoning with an average score of 90 vs 79.