GPT-4o vs GPT-4.1 nano

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

GPT-4o is clearly ahead on the aggregate, 60 to 23. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

GPT-4o's sharpest advantage is in mathematics, where it averages 66.9 against 9.8. The single biggest benchmark swing on the page is AIME 2024, 68 to 9.8. GPT-4.1 nano does hit back in knowledge, so the answer changes if that is the part of the workload you care about most.

GPT-4o is also the more expensive model on tokens at $2.50 input / $10.00 output per 1M tokens, versus $0.10 input / $0.40 output per 1M tokens for GPT-4.1 nano. That is roughly 25.0x on output cost alone. GPT-4.1 nano gives you the larger context window at 1M, compared with 128K for GPT-4o.

Quick Verdict

Pick GPT-4o if you want the stronger benchmark profile. GPT-4.1 nano only becomes the better choice if knowledge is the priority or you want the cheaper token bill.

Knowledge

GPT-4.1 nano

GPT-4o

53.8

GPT-4.1 nano

65.2

66
MMLU
80.1
66
GPQA
50.3
64
SuperGPQA
-
62
OpenBookQA
-
64
MMLU-Pro
-
1
HLE
-

Coding

GPT-4o
58
HumanEval
-
20
SWE-bench Verified
-
38
LiveCodeBench
-

Mathematics

GPT-4o

GPT-4o

66.9

GPT-4.1 nano

9.8

66
AIME 2023
-
68
AIME 2024
9.8
67
AIME 2025
-
62
HMMT Feb 2023
-
64
HMMT Feb 2024
-
63
HMMT Feb 2025
-
65
BRUMO 2025
-
80
MATH-500
-

Reasoning

GPT-4o
64
SimpleQA
-
62
MuSR
-
82
BBH
-

Instruction Following

GPT-4.1 nano

GPT-4o

82

GPT-4.1 nano

83.2

82
IFEval
83.2

Multilingual

GPT-4o
82
MGSM
-

Frequently Asked Questions

Which is better, GPT-4o or GPT-4.1 nano?

GPT-4o is ahead overall, 60 to 23. The biggest single separator in this matchup is AIME 2024, where the scores are 68 and 9.8.

Which is better for knowledge tasks, GPT-4o or GPT-4.1 nano?

GPT-4.1 nano has the edge for knowledge tasks in this comparison, averaging 65.2 versus 53.8. Inside this category, GPQA is the benchmark that creates the most daylight between them.

Which is better for math, GPT-4o or GPT-4.1 nano?

GPT-4o has the edge for math in this comparison, averaging 66.9 versus 9.8. Inside this category, AIME 2024 is the benchmark that creates the most daylight between them.

Which is better for instruction following, GPT-4o or GPT-4.1 nano?

GPT-4.1 nano has the edge for instruction following in this comparison, averaging 83.2 versus 82. Inside this category, IFEval is the benchmark that creates the most daylight between them.

Last updated: March 9, 2026

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