Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.
Nemotron Ultra 253B is clearly ahead on the aggregate, 50 to 28. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.
Nemotron Ultra 253B is the reasoning model in the pair, while Mixtral 8x22B Instruct v0.1 is not. That usually helps on harder chain-of-thought-heavy tests, but it can also mean more latency and more token spend in real use. Mixtral 8x22B Instruct v0.1 gives you the larger context window at 64K, compared with 32K for Nemotron Ultra 253B.
Pick Nemotron Ultra 253B if you want the stronger benchmark profile. Mixtral 8x22B Instruct v0.1 only becomes the better choice if knowledge is the priority or you need the larger 64K context window.
Nemotron Ultra 253B
43.5
Mixtral 8x22B Instruct v0.1
71.4
Nemotron Ultra 253B
34
Mixtral 8x22B Instruct v0.1
54.8
Nemotron Ultra 253B is ahead overall, 50 to 28. The biggest single separator in this matchup is MMLU, where the scores are 49 and 71.4.
Mixtral 8x22B Instruct v0.1 has the edge for knowledge tasks in this comparison, averaging 71.4 versus 43.5. Inside this category, MMLU is the benchmark that creates the most daylight between them.
Mixtral 8x22B Instruct v0.1 has the edge for coding in this comparison, averaging 54.8 versus 34. Inside this category, HumanEval is the benchmark that creates the most daylight between them.
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