o1-preview vs Mixtral 8x22B Instruct v0.1

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

o1-preview is clearly ahead on the aggregate, 83 to 28. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

o1-preview's sharpest advantage is in coding, where it averages 70.3 against 54.8. The single biggest benchmark swing on the page is HumanEval, 86 to 54.8.

o1-preview is the reasoning model in the pair, while Mixtral 8x22B Instruct v0.1 is not. That usually helps on harder chain-of-thought-heavy tests, but it can also mean more latency and more token spend in real use. o1-preview gives you the larger context window at 200K, compared with 64K for Mixtral 8x22B Instruct v0.1.

Quick Verdict

Pick o1-preview if you want the stronger benchmark profile. Mixtral 8x22B Instruct v0.1 only becomes the better choice if you would rather avoid the extra latency and token burn of a reasoning model.

Knowledge

o1-preview

o1-preview

78

Mixtral 8x22B Instruct v0.1

71.4

92
MMLU
71.4
90
GPQA
-
88
SuperGPQA
-
86
OpenBookQA
-
80
MMLU-Pro
-
32
HLE
-

Coding

o1-preview

o1-preview

70.3

Mixtral 8x22B Instruct v0.1

54.8

86
HumanEval
54.8
65
SWE-bench Verified
-
60
LiveCodeBench
-

Mathematics

o1-preview
94
AIME 2023
-
96
AIME 2024
-
95
AIME 2025
-
90
HMMT Feb 2023
-
92
HMMT Feb 2024
-
91
HMMT Feb 2025
-
93
BRUMO 2025
-
94
MATH-500
-

Reasoning

o1-preview
88
SimpleQA
-
86
MuSR
-
93
BBH
-

Instruction Following

o1-preview
88
IFEval
-

Multilingual

o1-preview
90
MGSM
-

Frequently Asked Questions

Which is better, o1-preview or Mixtral 8x22B Instruct v0.1?

o1-preview is ahead overall, 83 to 28. The biggest single separator in this matchup is HumanEval, where the scores are 86 and 54.8.

Which is better for knowledge tasks, o1-preview or Mixtral 8x22B Instruct v0.1?

o1-preview has the edge for knowledge tasks in this comparison, averaging 78 versus 71.4. Inside this category, MMLU is the benchmark that creates the most daylight between them.

Which is better for coding, o1-preview or Mixtral 8x22B Instruct v0.1?

o1-preview has the edge for coding in this comparison, averaging 70.3 versus 54.8. Inside this category, HumanEval is the benchmark that creates the most daylight between them.

Last updated: March 9, 2026

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