Claude 4.1 Opus vs GPT-4o

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

Claude 4.1 Opus wins overall with a score of 61 vs 56 (5 point difference).Claude 4.1 Opus wins 4 out of 4 categories.

Knowledge

Claude 4.1 Opus

Claude 4.1 Opus

74.5

GPT-4o

64.5

76
MMLU
66
76
GPQA
66
74
SuperGPQA
64
72
OpenBookQA
62

Coding

Claude 4.1 Opus

Claude 4.1 Opus

68

GPT-4o

58

68
HumanEval
58

Mathematics

Claude 4.1 Opus

Claude 4.1 Opus

75

GPT-4o

65

76
AIME 2023
66
78
AIME 2024
68
77
AIME 2025
67
72
HMMT Feb 2023
62
74
HMMT Feb 2024
64
73
HMMT Feb 2025
63
75
BRUMO 2025
65

Reasoning

Claude 4.1 Opus

Claude 4.1 Opus

73

GPT-4o

63

74
SimpleQA
64
72
MuSR
62

Frequently Asked Questions

Which is better, Claude 4.1 Opus or GPT-4o?

Claude 4.1 Opus scores higher overall with 61 vs 56, a difference of 5 points across all benchmarks.

Which is better for knowledge tasks, Claude 4.1 Opus or GPT-4o?

Claude 4.1 Opus leads in knowledge tasks with an average score of 74.5 vs 64.5.

Which is better for coding, Claude 4.1 Opus or GPT-4o?

Claude 4.1 Opus leads in coding with an average score of 68 vs 58.

Which is better for math, Claude 4.1 Opus or GPT-4o?

Claude 4.1 Opus leads in math with an average score of 75 vs 65.

Which is better for reasoning, Claude 4.1 Opus or GPT-4o?

Claude 4.1 Opus leads in reasoning with an average score of 73 vs 63.