Claude Opus 4.5 vs Mistral Large 2

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

Claude Opus 4.5 wins overall with a score of 79 vs 57 (22 point difference).Claude Opus 4.5 wins 4 out of 4 categories.

Knowledge

Claude Opus 4.5

Claude Opus 4.5

96

Mistral Large 2

66.5

99
MMLU
68
97
GPQA
68
95
SuperGPQA
66
93
OpenBookQA
64

Coding

Claude Opus 4.5

Claude Opus 4.5

91

Mistral Large 2

60

91
HumanEval
60

Mathematics

Claude Opus 4.5

Claude Opus 4.5

97.1

Mistral Large 2

67

99
AIME 2023
68
99
AIME 2024
70
98
AIME 2025
69
95
HMMT Feb 2023
64
97
HMMT Feb 2024
66
96
HMMT Feb 2025
65
96
BRUMO 2025
67

Reasoning

Claude Opus 4.5

Claude Opus 4.5

94

Mistral Large 2

65

95
SimpleQA
66
93
MuSR
64

Frequently Asked Questions

Which is better, Claude Opus 4.5 or Mistral Large 2?

Claude Opus 4.5 scores higher overall with 79 vs 57, a difference of 22 points across all benchmarks.

Which is better for knowledge tasks, Claude Opus 4.5 or Mistral Large 2?

Claude Opus 4.5 leads in knowledge tasks with an average score of 96 vs 66.5.

Which is better for coding, Claude Opus 4.5 or Mistral Large 2?

Claude Opus 4.5 leads in coding with an average score of 91 vs 60.

Which is better for math, Claude Opus 4.5 or Mistral Large 2?

Claude Opus 4.5 leads in math with an average score of 97.1 vs 67.

Which is better for reasoning, Claude Opus 4.5 or Mistral Large 2?

Claude Opus 4.5 leads in reasoning with an average score of 94 vs 65.