Qwen2.5-72B vs GPT-4.1

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Qwen2.5-72B is clearly ahead on the aggregate, 72 to 43. The gap is large enough that you do not need to squint at the spreadsheet to see the difference.

Qwen2.5-72B's sharpest advantage is in mathematics, where it averages 83.1 against 26.4. The single biggest benchmark swing on the page is AIME 2024, 86 to 26.4. GPT-4.1 does hit back in knowledge, so the answer changes if that is the part of the workload you care about most.

GPT-4.1 gives you the larger context window at 1M, compared with 128K for Qwen2.5-72B.

Quick Verdict

Pick Qwen2.5-72B if you want the stronger benchmark profile. GPT-4.1 only becomes the better choice if knowledge is the priority or you need the larger 1M context window.

Knowledge

GPT-4.1

Qwen2.5-72B

68.2

GPT-4.1

78.3

83
MMLU
90.2
82
GPQA
66.3
80
SuperGPQA
-
78
OpenBookQA
-
75
MMLU-Pro
-
11
HLE
-

Coding

GPT-4.1

Qwen2.5-72B

53.7

GPT-4.1

54.6

75
HumanEval
-
46
SWE-bench Verified
54.6
40
LiveCodeBench
-

Mathematics

Qwen2.5-72B

Qwen2.5-72B

83.1

GPT-4.1

26.4

84
AIME 2023
-
86
AIME 2024
26.4
85
AIME 2025
-
80
HMMT Feb 2023
-
82
HMMT Feb 2024
-
81
HMMT Feb 2025
-
83
BRUMO 2025
-
84
MATH-500
-

Reasoning

Qwen2.5-72B
80
SimpleQA
-
78
MuSR
-
81
BBH
-

Instruction Following

GPT-4.1

Qwen2.5-72B

85

GPT-4.1

87.4

85
IFEval
87.4

Multilingual

Qwen2.5-72B
84
MGSM
-

Frequently Asked Questions

Which is better, Qwen2.5-72B or GPT-4.1?

Qwen2.5-72B is ahead overall, 72 to 43. The biggest single separator in this matchup is AIME 2024, where the scores are 86 and 26.4.

Which is better for knowledge tasks, Qwen2.5-72B or GPT-4.1?

GPT-4.1 has the edge for knowledge tasks in this comparison, averaging 78.3 versus 68.2. Inside this category, GPQA is the benchmark that creates the most daylight between them.

Which is better for coding, Qwen2.5-72B or GPT-4.1?

GPT-4.1 has the edge for coding in this comparison, averaging 54.6 versus 53.7. Inside this category, SWE-bench Verified is the benchmark that creates the most daylight between them.

Which is better for math, Qwen2.5-72B or GPT-4.1?

Qwen2.5-72B has the edge for math in this comparison, averaging 83.1 versus 26.4. Inside this category, AIME 2024 is the benchmark that creates the most daylight between them.

Which is better for instruction following, Qwen2.5-72B or GPT-4.1?

GPT-4.1 has the edge for instruction following in this comparison, averaging 87.4 versus 85. Inside this category, IFEval is the benchmark that creates the most daylight between them.

Last updated: March 9, 2026

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