Claude 4.1 Opus vs Claude Opus 4.5

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

Claude Opus 4.5 wins overall with a score of 79 vs 61 (18 point difference).Claude Opus 4.5 wins 4 out of 4 categories.

Knowledge

Claude Opus 4.5

Claude 4.1 Opus

74.5

Claude Opus 4.5

96

76
MMLU
99
76
GPQA
97
74
SuperGPQA
95
72
OpenBookQA
93

Coding

Claude Opus 4.5

Claude 4.1 Opus

68

Claude Opus 4.5

91

68
HumanEval
91

Mathematics

Claude Opus 4.5

Claude 4.1 Opus

75

Claude Opus 4.5

97.1

76
AIME 2023
99
78
AIME 2024
99
77
AIME 2025
98
72
HMMT Feb 2023
95
74
HMMT Feb 2024
97
73
HMMT Feb 2025
96
75
BRUMO 2025
96

Reasoning

Claude Opus 4.5

Claude 4.1 Opus

73

Claude Opus 4.5

94

74
SimpleQA
95
72
MuSR
93

Frequently Asked Questions

Which is better, Claude 4.1 Opus or Claude Opus 4.5?

Claude Opus 4.5 scores higher overall with 79 vs 61, a difference of 18 points across all benchmarks.

Which is better for knowledge tasks, Claude 4.1 Opus or Claude Opus 4.5?

Claude Opus 4.5 leads in knowledge tasks with an average score of 96 vs 74.5.

Which is better for coding, Claude 4.1 Opus or Claude Opus 4.5?

Claude Opus 4.5 leads in coding with an average score of 91 vs 68.

Which is better for math, Claude 4.1 Opus or Claude Opus 4.5?

Claude Opus 4.5 leads in math with an average score of 97.1 vs 75.

Which is better for reasoning, Claude 4.1 Opus or Claude Opus 4.5?

Claude Opus 4.5 leads in reasoning with an average score of 94 vs 73.