Claude Opus 4.5 vs Nova Pro

Side-by-side benchmark comparison across knowledge, coding, math, and reasoning.

Quick Verdict

Claude Opus 4.5 wins overall with a score of 79 vs 32 (47 point difference).Claude Opus 4.5 wins 4 out of 4 categories.

Knowledge

Claude Opus 4.5

Claude Opus 4.5

96

Nova Pro

38.8

99
MMLU
41
97
GPQA
40
95
SuperGPQA
38
93
OpenBookQA
36

Coding

Claude Opus 4.5

Claude Opus 4.5

91

Nova Pro

33

91
HumanEval
33

Mathematics

Claude Opus 4.5

Claude Opus 4.5

97.1

Nova Pro

40

99
AIME 2023
41
99
AIME 2024
43
98
AIME 2025
42
95
HMMT Feb 2023
37
97
HMMT Feb 2024
39
96
HMMT Feb 2025
38
96
BRUMO 2025
40

Reasoning

Claude Opus 4.5

Claude Opus 4.5

94

Nova Pro

38

95
SimpleQA
39
93
MuSR
37

Frequently Asked Questions

Which is better, Claude Opus 4.5 or Nova Pro?

Claude Opus 4.5 scores higher overall with 79 vs 32, a difference of 47 points across all benchmarks.

Which is better for knowledge tasks, Claude Opus 4.5 or Nova Pro?

Claude Opus 4.5 leads in knowledge tasks with an average score of 96 vs 38.8.

Which is better for coding, Claude Opus 4.5 or Nova Pro?

Claude Opus 4.5 leads in coding with an average score of 91 vs 33.

Which is better for math, Claude Opus 4.5 or Nova Pro?

Claude Opus 4.5 leads in math with an average score of 97.1 vs 40.

Which is better for reasoning, Claude Opus 4.5 or Nova Pro?

Claude Opus 4.5 leads in reasoning with an average score of 94 vs 38.